Brain-Icon1 The need

Cognitive Needs Throughout Life
Brain health is one of the major public health concerns of all ages. From children and students, who are developing in a highly competitive academic environment, and whose parents are committed to supporting their mental performance and academic achievements, to seniors seeking to prevent the loss of cognitive skills and abilities, occurring as part of the natural aging process.

Sport-Icon2 Why ps ?

Lipids are a major component of brain tissue. A full 60% (dry weight) of our brain is made of lipids, and phospholipids are among the most important of those components. Compared to other organs, PS is especially prevalent in the brain. For example, PS makes up only about 3% of liver and heart phospholipids, whereas it makes up 18% of the phospholipids in the brain. This high level of PS in membranes of the brain highlights its importance for proper brain structure and function. PS was shown to increase neurotransmitter secretion in the brain, as well as improve neuron survival and affect mechanisms responsible for learning and formation of memories (Tsakiris S et al.  The Biochemical journal. 1984;220:301-307; Akbar M et al. Proceedings of the National Academy of Sciences of the United States of America. 2005;102:10858-10863). Indeed, numerous clinical studies with PS demonstrate the effect of PS intake on enhancement of cognition – especially memory and sharp thinking, enhance concentration and learning, support of cognitive skills and abilities and more. Benefits of PS were demonstrated in many populations, from elderlyto children and students (Glade & Smith, Nutrition. 2015 Jun;31(6):781-6)

PS is the only dietary ingredient with cognitive health claims qualified by the FDA:

FDA has allowed for inclusion of a qualified health claim on PS products. Being Qualified Health Claims, these come together with a disclaimer as follows:

  • “Consumption of phosphatidylserine may reduce the risk of dementia in the elderly”**Very limited and preliminary scientific research suggests that phosphatidylserine may reduce the risk of dementia in the elderly. FDA concludes that there is little scientific evidence supporting this claim.”
  • “Consumption of phosphatidylserine may reduce the risk of cognitive dysfunction in the elderly”**Very limited and preliminary scientific research suggests that phosphatidylserine may reduce the risk of cognitive dysfunction in the elderly. FDA concludes that there is little scientific evidence supporting this claim.”

Cognitive Benefits of PS for Older People

  • The world’s population is aging. It is expected that by 2050 about 15% of the global population will be over the age of 60, while in some countries, such as USA, Australia, China and others, people over 60 years of age are expected to make up more than 20% of the population, while in other countries, mainly Japan, Italy , Germany and other European countries, elderly are expected to make 40% of the population, affecting every aspect of life in these countries. Many of the elderly suffer from age-related cognitive decline.

PS Cognitive Benefits for the Aging Population

  • A significant number of clinical studies have examined the effects of PS intake on cognitive function of the elderly. In these studies PS was found to have cognitive benefits on memory, attention, vigilance, concentration, daily living activities, communication and socialization, and more (Glade & Smith, Nutrition. 2015 Jun;31(6):781-6)

For example, in a clinical study that was made in Japan, a dose of 100 mg/day of PS for 6 months was linked to improvement in various cognitive function endpoints. The effect was sustained for at least 3 months after termination of PS intake, demonstrating the long-term effect of PS intake (Kato – Kataoka A. et al. J Clin Biochem Nutr 2010; 47, 246-255).

In another clinical study,  elderly people were given Sharp•PS® for a period of 3 months. Some cognitive capabilities, mainly memory, improved after a 6-week period, while other capabilities improved after 12 weeks of supplementation (Richter Y et al.  Clinical interventions in aging. 2013 8, 557-563).

PS Cognitive Benefits for high school students

  • to demonstrate that PS ingestion is not only helpful for elderly people, its effect on cognitive function of high school students was demonstrated following 40 days of supplementation with 100 mg/day of PS in milk. The results showed beneficial effects on memory, attention, learning and more (Yong T. et al. Chongqing Medicine 2011 40, 3022-3023).

Why Sharp•PS®?

The most common dietary ingredients used to improve cognitive function are phosphatidylserine (PS), DHA and Ginkgo Biloba. PS and DHA are similar in that they are both important building blocks of the brain and their effects are long-lasting. The main differences between them are that DHA has poor organoleptic properties, while PS can be consumed in any form with no problematic organoleptic issues. In addition, the required effective dosage of DHA is very high, while the effective dosage of PS can easily be reached. Ginkgo Biloba is somewhat different, as it is not natural to the human body and its effect is short-term. It is important to note that PS is the only dietary supplement ingredient that has been identified by the FDA as eligible for a cognitive qualified health claim.

Why Sharp•PS®?

  • Sharp•PS® is one of the leading phosphatidylserine brands in the supplement industry, representing highest quality and greatest variety of grades in the world
  • Sharp•PS® has exclusive and patented grades
  • Sharp•PS® is produced from a variety of sources (soy, sunflower, fish) and grades especially suitable for food applications
  • Excellent organoleptic properties, easy to use in tablets, sachets, gummies, powder products and more
  • Sharp•PS® has wide regulatory coverage

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