A CLINICALLY PROVEN NATURAL NUTRIENT
Increasing numbers of people report mood changes that leave them feeling despondent or “blue” at some point in their lives. This is especially common among older people and among women. Whether experienced as a short-lived problem or a long-term condition, such gloomy feelings affect people’s ability to function properly in their jobs, studies and personal lives.
PS eases negative moods that may occur from time to time in response to life’s stressors
Phosphatidylserine (PS), a naturally-occurring lipid that is found throughout the body, has been clinically shown to improve mood. PS intake has been shown to reduce levels of the stress hormone, cortisol, which naturally occurs as part of the body’s reaction to negative mood changes.
Clinical studies with PS have shown the ingredient to have positive effects on mood (Gindin, Y. et al Gerontologist 193, 1 1993; Benton, D. et al, Nutr Neurosci 4, 169-178 (2001).).–
Cortisol levels are increased in people that are experiencing a low mood. Research has shown that PS intake was linked to reductions in cortisol levels in both blood and saliva (Hellhammer, J. et al. Stress 7, 119-126 (2004).; Starks, M. A. et al. J Int Soc Sports Nutr 5, 11, (2008).; Baumeister, J et al.. Nutr Neurosci 11, 103-110, (2008)
Consumption of PS was linked to improved mood in the elderly
Elderly people are often bothered by feelings of occasional gloom. In a double-blind, placebo-controlled study involving 57 elderly subjects who consumed PS (300 mg/day) for 12 weeks, there was almost no development of “winter blues”, while those with no PS intake suffered from a significant reduction in their mood (Gindin, Y. et al. The Gerontologist 193, 1 (1993)).
Effect of Sharp•PS® and DHA (Sharp•PS®-Silver) on mood in older age
In a pilot study of 18 late-age elderly people experiencing low mood, participants consumed a combination of PS (300 mg/day) and omega-3 (570 mg/day) (Sharp•PS® silver) for 12 weeks, and were administered a validated test of their mood status. PS administration was associated with a pronounced mood improvement (Komori, T.. Mental Illness 7, 7-11 (2015)).
As discussed above, the dose of PS shown to improve moods is 300 mg/day. Clinical studies with PS intake have shown effects after 12 weeks of consumption. Some clinical studies have shown further mood improvement when combining PS with omega-3. While PS is a dietary ingredient that may be useful for those who are in a gloomy state, it is not recommended as a drug for those suffering from Major Depressive Disorder (MDD). MDD is considered a disease and should be treated by trained professionals.